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Beilstein J. Org. Chem. 2015, 11, 469–472, doi:10.3762/bjoc.11.52
Graphical Abstract
Scheme 1: PPN pyrophosphate.
Scheme 2: Preparation of NDPs.
Scheme 3: 31P NMR spectrum of TDP 2a after precipitation from reaction mixture.
Scheme 4: Attempted use of an isopropylidene-protected 5’-tosylnucleoside.